The Hawaii HIDTA consists of 15 primary initiatives which are structured into 14 enforcement task forces, four intelligence initiatives within the Investigative Support Center (ISC), and four additional management, support, prevention and training initiatives.

The Hawaii HIDTA facilitates cooperation and collaboration among multiple law enforcement organizations operating within the region. Cooperation and collaboration among initiatives and agencies is a common practice in the program and results in successful arrests, seizures, disruptions, and dismantling of drug trafficking organizations (DTOs). The accomplishments of each initiative and task force are significant components of an aggregate picture of the program-wide accomplishments at a regional level. These regional aggregate accomplishments culminate into a National HIDTA Program success in combating the drug problems facing the nation.